Special feature of 1905 film network The appearance with a sense of high quality is one of her most eye-catching labels.Walking pictorial, the darling of fashion, became the cover queen of fashion magazines at home and abroad that year.But she is an actress, with a variety of customs and styles.She is.

Red lips with printed brocade cheongsam are graceful and pretty, without losing the charm of Qinhuai River women.

stage photo

Smoke waves flow, gestures are amorous feelings. From the eyes to the manners, it is full of flavor.He once said: "To let her play Yumo is to take a fancy to her unique temperament."

After three years of secret training, she portrayed Yumo’s mature and charming, intellectual atmosphere, meticulous, dusty and unconventional, beautiful and forbearing image, which made the original author Yan Geling full of praise.

"flowers of war" stills

In 2011, flowers of war, which won 600 million box office and became the annual Chinese box office champion, made NiNi, a 23-year-old fledgling, debut at the peak.

She has a variety of amorous feelings, and she will never be able to avoid beauty again.Her beauty is ever-changing, which can be pure and vivid.In school, NiNi, wearing a white sports school uniform, is so pure and lovely, gentle and clever, and the anise played by NiNi bears the imprint of youth, which reminds us of the youth that was shining and full of regret.

Stills of "In a hurry that year"

Long hair fluttering, beautiful in the park, she has also become a beautiful Zi Xia, smiling is full of aura.

Stills of Wukong Biography

Wearing a red dress and red lips, in the TV series "last romance", Ni Nihua is an intellectual and capable, confident and generous workplace elite Zhu Suosuo, which perfectly interprets the sentence adapted from Yi Shu’s original work: "A woman among women is dazzling."

Tv series "precious times of the past"stills

In the suspense movie, Nini is transformed into a three-faced Jiang Yuee, whose beautiful and devoted eyes are pure girls, and her cold and sharp temperament is a young woman in Leng Yan, and she is also a caring and loving mother full of tears.

Stills of "Kill"

In the TV series "Chen Xi Yuan" starring NiNi, Ni Ni performed the life of the heroine "Sansheng Sanshi" in three different states:

The spirit of the first life is lively and outgoing; Lin Mo, the second Sargam, was warm as the wind, and Ling Xi, the third, vividly interpreted the pull of humanity and divinity after returning from robbery.

Stills of TV series "Chenxiyuan"

But Ni Ni is far more than beautiful, and she can be soft and rigid.Dressed in a national costume, with a short ear-length hair, it is a combination of skill, intelligence and courage.

In the movie, NiNi lost her long hair, concealed her proud figure, and hid all kinds of amorous feelings, playing Wang Huiwu, a revolutionary figure who ran for women’s liberation, and gained an independent female force.

"1921" stills

Chivalrous women are classic and important roles in all the films, including feminine and beautiful women, heroic and rigid men, and the iron dragonfly in the movies is no exception.

"daoist magic" stills

NiNi’s heroic iron dragonfly is not only domineering, but also introverted.

In "daoist magic", she was not trapped by the face value and was not afraid of the ugliness in the play. She appeared as an ugly girl with buckteeth, and showed the rude and free-spirited side of the iron dragonfly just right. When she took off the human skin mask, the ugliness and beauty were extremely full, which was even more amazing.

Zhang Yimou once commented on NiNi: "I think she is a new type of a new era, and her future is limitless."Behind the halo, it is more of her own efforts.

NiNi and three powerful actors, Zhang zhen, and Wang, compete on the same stage, which not only has not been overshadowed, but also adds a purer stroke to the film 2.

Stills of Snow Storm

In Snowstorm, the role of doctor Sun Yan is to illuminate all crazy people. In the play, her dedication also made the crew members who performed together admire her.NiNi tried many times to go to the operating room, learn professional skills from doctors, and integrate himself into the role of forest doctors.

"Desperate Saburo" Zhang zhen said that NiNi worked harder than him, practicing more than 20 times for the lines of one word.The suffocating cold under the snowstorm can show the ultimate human nature.　

Stills of Snow Storm

When NiNi was filming a night scene where the car was trapped in a snowy mountain, the trunk of the car was open at MINUS 30 degrees, and the blower kept blowing at her for the manufacturing effect, but she still insisted on shooting it again and again.

Pang Ling, played by NiNi, is indispensable in the film. Even if sandwiched between two film emperors, NiNi’s performance is impressive.

Shock Wave 2 stills

After receiving the task from the boss, quickly seize the opportunity to make an action plan and lend a helping hand to the old love caught in the mud; At the scene of the action, we decided to suppress the pain in our hearts and issued orders in an orderly manner.

Shock Wave 2 stills

When you are sharp, you don’t want a man, and your tenderness is touching.

Shock Wave 2 stills

For more than ten years, the constantly polished acting skills are gradually pushing her forward, and the female role she plays is far more than just beauty.However, in this decade, there has never been a masterpiece in NiNi that can overshadow the light of flowers of war. For actresses, this is cruel.

Ni Ni once said: "I want to be an acting school, like an actor, and be remembered by the audience through superb acting, because beauty can’t last long."More and more excellent works make NiNi not only recognized for its beauty, but also for its advanced beauty.

Today, she loves the stage and fears the performance, and she is still quietly accumulating strength and waiting for opportunities.On the afternoon of December 11th, Movie Channel Shadow Man 1+1 will broadcast Snow Storm starring NiNi and Shock Wave 2, and NiNi, who is courageous and heroic, is worth looking forward to!

introduction

Sudden cardiac death is one of the most important problems faced by cardiologists. In many cases, the success rate of rescue is not high, so the mortality rate is still high. At present, most of the solutions are passive, and ICD (Implantable Defibrillator) is installed after patients survive, but the status quo of diagnosis and treatment of sudden cardiac death (SCD) is not optimistic. In this regard, Fuwai Hospital of China Academy of Medical SciencesProfessor Hua Wei.Report on "Current situation and challenges of prevention and treatment of sudden cardiac death in China".He mentioned that early defibrillation is the key to improve the survival rate of cardiac arrest, and early preventive implantation of ICD is the most effective means to prevent sudden cardiac death.

Sudden cardiac death is the first killer of cardiovascular disease.

The leading cause of death among adults in the United States is SCA (cardiac arrest), with an annual incidence of 450,000, which exceeds the sum of all these diseases, such as stroke (167,366), lung cancer (157,400), breast cancer (40,600) and AIDS(42156).

As a populous country, how many people have sudden cardiac death every year in China? Fuwai Hospital conducted an epidemiological survey more than ten years ago, and included the population of Beijing, Guangzhou, Shanxi and Xinjiang for sampling survey. It was the first time that the incidence of SCD in China was 418.4/100,000. If calculated by the population of 1.3 billion, the total number of sudden deaths in China was about 544,000/year, ranking first in the world.

The concept of sudden cardiac death

Definition: Sudden death due to heart causes is characterized by quickness, natural and unexpected within 1 hour after symptoms occur. About the etiology of SCA, 80% are coronary heart disease, chronic myocardial scar after myocardial infarction, acute plaque instability, rupture, bleeding and thrombosis. 10-15% are cardiomyopathy, including hypertrophic cardiomyopathy and dilated cardiomyopathy. Less than 5% of uncommon causes, such as primary electrical activity and hereditary ion channel abnormality, valvular disease or congenital heart disease, and other reasons. The triggering mechanism of SCA: transient ischemia, hemodynamic fluctuation, neurocardiovascular influence and environmental factors.

Prevention and treatment of sudden cardiac death-first aid outside the hospital

First aid outside the hospital:

Timely cardiopulmonary resuscitation and electrical defibrillation;

Most patients can not get timely and effective cardiopulmonary resuscitation;

The data shows that the popularity and effect of SCD out-of-hospital first aid are not good; According to the data of the United States in 2004, there were 166,000 cases of sudden cardiac death outside the hospital. Among them, only about 60% received emergency medical services, and the average survival rate after rescue was only 6.4%.

The above data may be lower in China.

Electrical defibrillation should be performed as soon as possible for patients with sudden cardiac death. Early defibrillation is the key to improve the survival rate of cardiac arrest.

Promote the use of AED (automated external defibrillator) in public areas with relatively high probability of witness cardiac arrest. Try to shorten the interval between stopping pressing and giving electric defibrillation, and CPR must be resumed immediately after giving electric defibrillation.

In 2010, JACC magazine reported the comparison of survival rate between CPR alone and CPR+AED for SCD patients outside the hospital. 13769 cases of SCD were selected, and only CPR was given before EMS arrived, with a survival rate of 9% (382/4 403). The survival rate was 24%(69/289) after CPR+AED treatment before EMS arrived, which was more than 2 times higher. Logistic regression results show that:AED therapy was significantly related to the survival rate of SCD patients, and the OR value was 1.75(p<0.002).

Current situation of AED configuration in China

At present, the number of defibrillators installed in public places in China is very limited, and fewer people know how to use them, which makes many patients lose the opportunity of first aid. It is difficult to carry around and play a role in time. It is impossible to issue treatment before the patient has syncope, which reduces the damage of important organs.

Prevention and Treatment of Sudden Cardiac Death —— Application of Wearable Defibrillator (WCD)

WCD can monitor the heart rhythm in real time. Once a patient has ventricular fibrillation, it can identify ventricular fibrillation in the shortest time, deliver electrode defibrillation, and effectively save the patient’s life. Automatic glue spraying during defibrillation; No conductive paste, no sticky electrode sheet; Light weight (the wearing part is only 0.815 kg); Make patient’s conscious judgment before defibrillation; Bidirectional wave 150 joules; Record and save the data 30 seconds before the heart event; Store ECG data for up to 75 minutes at a time.

AHA medical advice:

WCD technology has also been preliminarily studied in China. From June 2018 to October 2019, Fuwai Hospital and several hospitals jointly led a multi-center clinical observation study on wearable defibrillators in China. 54 patients with WCD were enrolled,Baseline information is as follows:

Indications of WCD under study:

1. Early acute myocardial infarction (within 40 days) with LVEF≤35%, 19 cases (35.2%).

2. 9 cases (16.7%) were waiting for heart transplantation and had high risk of SCD.

3. ICD could not be implanted temporarily for various reasons (such as infection), 7 cases (13.0%).

4. Newly diagnosed non-ischemic cardiomyopathy with LVEF<35%, 5 cases (9.3%).

5. Five cases (9.3%) met the secondary prevention of SCD, but the estimated survival time was less than one year.

6. ICD implantation was refused for various reasons (such as economy), 5 cases (9.3%).

7. After emergency revascularization (within 3 months), LVEF≤35%, 4 cases (7.4%).

Follow-up

1. Average wearing days: 51 34 days (longest 145 days, shortest 1 day);

2. Only 18 patients (33.3%) insisted on wearing it for one month during the three-month follow-up;

3.59.3% patients feel good about wearing; 33.3% feel ordinary when wearing;

4. The two main problems of wearing are the influence, and the size does not meet the requirements of its own body shape;

5. Only one patient was monitored for ventricular fibrillation (successful defibrillation);

6. Error-free discharge occurs.

The most effective means to prevent sudden cardiac death-implantable defibrillator (ICD)

In the United States, the annual incidence of sudden cardiac death is 250,000 to 350,000, and the average survival rate is only 5%. It is necessary to identify this high-risk patient to prevent cardiac arrest. Data show that ICD is as effective as 99% in the treatment of cardiac arrest. At the earliest, ICD needed open chest implantation, and now there are many jugular vein implants.

The progress of ICD treatment: the first ICD was implanted in the United States in 1980, approved by FDA in 1985, simple program control in 1987, hierarchical treatment in 1988, non-thoracotomy electrode lead system in 1989, biphasic ICD system in 1989, chest ICD system in 1993, unipolar defibrillation in 1993, miniaturization in 1993-1997, prolonged life and improved diagnostic ability. Now it has become a widely used method to prevent sudden cardiac death.

2017 ACC/AHA/HRS Guidelines for Patients with Ventricular Arrhythmia Management and SCD Prevention

Class I indications:

1. Survivors of SCD caused by ischemic heart disease, ventricular tachycardia or ventricular fibrillation, or stable ventricular tachycardia caused by hemodynamic instability or irreversible factors, with an estimated survival time of > 1 year, ICD implantation is recommended.

2. In patients with ischemic heart disease and syncope, if electrophysiological examination induces monomorphic sustained ventricular tachycardia and the expected survival time is more than 1 year, ICD implantation is recommended.

3. If the LVEF of ischemic heart disease is less than 35%, at least 40 days after myocardial infarction, or 90 days after revascularization, if the cardiac function is still Grade II or III on the basis of drug treatment guided by the guidelines, ICD is recommended for primary prevention.

Although ICD is a type I indication, it also has defects. After ICD is implanted in human body, its utilization rate is not very high. A prospective, non-randomized international multi-center clinical study of so-called level 1.5 prevention enrolled 3889 patients in 17 countries.

Level 1.5 prevention = level 1 prevention plus one or more items:

Non-persistent ventricular tachycardia; Frequent ventricular premature beats (> 10 beats/hour); LVEF<25%； History of syncope.

The results showed that the average follow-up was 21 10 months. Compared with the patients who did not receive ICD implantation, the all-cause mortality of the patients who received ICD implantation decreased by 49%.

The application of ICD in China, the first epicardial ICD system was implanted in 1992, and the first intravenous ICD system was implanted in China in 1996. With the formulation of ICD implantation indication guidelines and publicity and education, the number of implants has increased greatly every year since 2002. At present, about 5000-6000 patients are implanted with ICD every year in China. The proportion of primary prevention and secondary prevention in patients with ICD implantation in China is equal.

Difficulties that traditional intravenous ICD system may encounter;

Subclavian vein occlusion;

Vascular malformation;

Wear of venous lead (broken lead/broken insulation);

Difficult to pull out the lead (infection and other reasons);

The whole system needs to be removed due to infection.

In order to reduce and avoid complications caused by defibrillation leads via intravenous ICD electrodes, a brand-new technology "total subcutaneous ICD" has been developed. Vein-free lead defibrillation system, subcutaneous implantable ICD system, total subcutaneous implantation. There is no need to implant electrode leads into the heart through blood vessels to ensure the structural integrity of blood vessels. Implantation is strictly in accordance with anatomical structure, and radioscopy is not needed during implantation. The disadvantage is that pacing is not possible.

On December 23, 2014, Fuwai Hospital implanted the first SICD in China.

In 2015, ESC Guidelines recommended its Class Ⅱa:

For patients with ICD indications who do not need pacing, CRT or ATP treatment, S-ICDs should be considered as an alternative treatment for intravenous ICD.

2017 AHA/ACC/HRS VA/SCD guidelines will transfer it to Class I indications, but there are conditions: 　

"Implanting a subcutaneous cardioverter defibrillator (S-ICD) has a lower risk of infection than TV-ICD. Therefore, S-ICD is more suitable for patients with high risk of infection, such as patients with device infection, patients with end-stage renal disease, or patients with long-term immunosuppression. "

Multi-center SICD research in China and follow-up analysis of clinical application in multi-centers in implantable cardioverter defibrillator under the skin included 111 patients who successfully implanted S-ICD in 42 centers in China and had stable follow-up. The follow-up period was (272 283) d, with 39 cases of primary prevention (35.1%) and 72 cases of secondary prevention (64.9%). The results showed that 22 patients (20.8%) received 51 appropriate defibrillation treatments, and 9 patients (8.5%) had 24 inappropriate defibrillation treatments. The main cause of inappropriate defibrillation is t-wave oversensing. It is suggested that S-ICD implantation is effective and safe in China.

NEJM magazine published a prospective randomized controlled study of PRAETORIAN. This is the first prospective randomized controlled head-to-head study of S-ICD vs TV-ICD. There are 849 patients enrolled in 39 centers (Europe and the United States) in 6 countries, including 426 cases of S-ICD and 423 cases of TV-ICD. All products of TV-ICD can be enrolled (single cavity ICD), with ICD indications and meeting the requirements of S-ICD implantation.

Main end point:Compared with TV-ICD, S-ICD has non-inferiority, inappropriate electric shock, complications related to ICD system and needing intervention, and lead-related complications.

Main results:The incidence of inappropriate treatment and complications of S-ICD is similar to that of TV- ICD. The mortality of S-ICD & TV-ICD is low; The lead-related complications were significantly reduced, with 6.6% (n=24) in the control group (TV-ICD) and 6.6%(n=24) in the control group (TV-ICD).

The future and development prospect of SICD. The disadvantage of full subcutaneous ICD is that it can not effectively pace the heart. If the patient has bradycardia, he can pace bradycardia with the help of a leadless pacemaker.

Another feasible scheme, EV-ICD,Defibrillation coil is under the sternum, closer to the heart, and can conduct effective cardiac pacing. The purpose of research and development is to realize low defibrillation threshold (DFTs), small size, long service life and pacing function including ATP (anti-tachycardia pacing) through EV-ICD. This technology has been clinically studied.

EV-ICD research is a prospective, non-randomized, first long-term clinical study in human body. Patients who meet the indications of class ⅰ or ⅱ A ICD were included; Under fluoroscopy, the defibrillation lead was buried in the posterior sternum area by subcutaneous tunnel tool, and the pulse generator was placed on the left side of the chest. The defibrillation efficiency was tested by inducing fibrillation during implantation, detecting and converting ventricular fibrillation. The energy to terminate ventricular fibrillation was usually 20J once or 30J； twice in succession. Follow-up was performed at 2 weeks, 4-6 weeks and 3 months after operation. The main safety end point was no instrument or operation-related complications within 3 months after operation.

The results showed that 21 patients tried to implant, and finally 20 patients successfully implanted EV-ICD；. One patient with mediastinal fibrosis failed to be implanted successfully.

Defibrillation therapy:One patient failed to induce ventricular fibrillation/tachycardia; 89.5% patients (17/19 cases) successfully terminated ventricular fibrillation, and the defibrillation threshold was ≤30J, and the median defibrillation threshold was 15J；. The defibrillation threshold of 10.5% patients was > 30J.

Bradycardia treatment:95% patients (19/20 cases) successfully completed the pacing test, and the pacing threshold in acute phase was ≤10V, with an average of 5.1±1.9V；; R wave perception test: the average amplitude of R wave is 3.2±1.7mV；; The amplitude of R wave during ventricular fibrillation is 2.8±1.7mV, and ventricular fibrillation during operation can be correctly identified.

EV-ICD studies the clinical application experience of long-term implantation of infrasternal extravascular ICD, which proves that EV-ICD overcomes the shortcoming that SICD can’t pace, and will have a wider application prospect.

summary

Sudden cardiac death should attract our attention. The prevention and treatment of sudden cardiac death in China has a long way to go, and we need all of you to work together to reduce the occurrence of SCD in China and save more patients.

-End-　

　　The 46-episode drama "Old Tavern", starring Chen Baoguo and Amanda, tells the story of Chen Huaihai, the shopkeeper of the Shandong Old Tavern on Dalian Haoren Street, and what happened in the old Tavern he opened. Since its launch, the drama has won the love of many audiences with its rich chronological texture, solid and excellent plays, rich and full characterization and witty lines.　

　　If "Braving the Kanto" in those days was a comprehensive review of the real population migration in the history of China, today’s "Old Pub" is a multi-dimensional extension and upgrading expression of Gao Mantang’s great feelings of the "post-Braving the Kanto era" with a brand-new story context after ten years of precipitation.　　　

　　"Something nutritious for young people"

　　Today, nearly half of Dalian’s population comes from Shandong. Gao Mantang’s ancestors came to Dalian from his grandfather’s generation, and his father opened a pub on Xinglong Street in Dalian, from which the story of Old Pub originated. Gao Mantang’s deepest memory is the wonderful time after his father drank alcohol when he was a child: "My father always plays his broken erhu after drinking. Singing" Empty City Strategy "is beautiful, and singing" Xu Ce Running the City "is almost enough. If there is another Shandong Lu Opera, it is almost time to sleep." Gao Mantang’s creative desire was inspired by the legendary life stories and chivalrous feelings of his father’s wandering drinkers: "Write the stories of his father’s time with ease, and the more you write, the more energetic you are."

　　"One Lushunkou, half a modern history", with reverence for history, at the centenary of his father’s birthday, Gao Mantang finally set out to write this story that has been in his mind for thousands of times. The Old Pub was written from the national crisis in China in 1928 to 1949. Gao Mantang thought that the history of suffering in it should not be forgotten: "We should not only cherish the future, but also review the history, and remind the young people of today that when they are enjoying their lives, it is necessary for us as artists to bring them something nutritious."

　　The old pub in the play has undergone great changes for half a century, and it has been renamed several times in different years. Finally, in 2013, the name of "Shandong Old Pub" was reused. Such an old name is actually a continuation of tradition, which implies the spiritual inheritance of Do not forget your initiative mind. The Old Pub is a touching letter written by Gao Mantang to his father, a memorial to the city of Dalian, and a long and meaningful romantic poem dedicated to the audience.

　　"Everyone is in my blood."

　　In the play, Chen Huaihai is undoubtedly the most eye-catching: being a father at home and caring for his wife and children; Being a shopkeeper in a pub, caring for brothers; In Haoren Street, it is the backbone, helping the poor; He is the core of The Old Tavern and the backbone of the Chinese nation. As a descendant of the "Go to the East" people, Gao Mantang bluntly said: "I can’t educate the audience, I can only use my artistic image to infect the audience, enrich the modern people with these characteristics of Chen Huaihai, and let the traditional spirit return to our new era."

　　Chen Baoguo, who won the Flying Award for "The Old Farmer" in 2015, expressed deep gratitude to Gao Mantang at the award ceremony: "Mr. Mantang, your play is difficult to perform but long-term, and your play is an actor." For Chen Baoguo, Gao Mantang is a predecessor, a Bole, and a noble person in his artistic career; Similarly, Gao Mantang regarded him as a close friend and a soul mate in his creation. After ten years’ cooperation, they left many excellent works, and this time, The Old Tavern is a tailor-made work by Gao Mantang for Chen Baoguo. In the early stage of script creation, he had confided in Chen Baoguo many times and told him many archetypal characters and real history behind the script, which made this story take root in Chen Baoguo’s heart.

　　On the basis of Chen Huaihai as the core, The Old Tavern closely links personal destiny with feelings of home and country through group narration, and staged a legendary drama of "Every man is responsible for the rise and fall of the world". In Gao Mantang’s view, "Everyone in this room is in my blood. Chen Huaihai is equivalent to a solid main line and hub. The drinkers who come and go are branches that crisscross and merge with each other. These characters can open and close freely. "

　　"Creation should go deep into life"

　　Gao Mantang is a "rough man" born and raised in Northeast China. He has a hard-working nature in his bones. He visited six provinces and interviewed more than 200 talents to complete an old farmer. He is willing to stay in the steel plant for three years for the material of steel workers in The Age of Steel and The Great Craftsman. "Going to the East" lasted for ten years, spanning the three provinces of Heilongjiang, Kyrgyzstan and Liaoning, and reaching Jiaodong and Southwest Shandong, with a journey of tens of thousands of kilometers. In a bitter and cold place, you can only eat tofu with soy sauce to satisfy your hunger. In this regard, Gao Mantang has his own stubborn insistence: "Creation should go deep into life, take off on a solid land, and grab a handful of soil like an eagle."

　　In the pursuit of short and fast experience, creation is becoming more and more fragmented and flowing. Gao Mantang lamented this: "Such a story is too empty, not solid, and it is a suspended story. Life is the source of creation. Only by feeling, touching and experiencing can we have the impulse to create. I am willing to slow down the creative speed. With originality, China’s TV series will have long-term vitality. " (Qilu Evening News Qilu Yidian Special Reporter Tang Poetry)

twelveOne day at the end of the month:

In the morning, I just saw a case of pneumonia infected by novel coronavirus in Wuhan on the Internet, and I heard some comments in the department, but after all, Wuhan is still a little far from Beijing, and everyone didn’t pay much attention to it. When the shift is over in the morning, the director of the department and the head nurse will remind everyone that we should strictly implement the fever screening process at work, do a good job of self-protection, wear a mask at work and wash our hands frequently.

oneMid-June

In January, the epidemic situation gradually escalated, and the situation was grim. My heart was a little drummed. It was a very sad experience for both patients and medical staff to suffer from infectious diseases.onemoon14No.1 began to receive the notice of prevention, control and supervision of infectious diseases issued by higher authorities. The department leaders attached great importance to it and repeatedly emphasized the prevention and control work, and the medical staff in the department paid more and more attention.

17Years ago, I experiencedSARS. And these young nurses were still in primary school. As a head nurse and an old nurse, I will share my past experiences with them every morning when my shift is over. When I am moved, my eyes are full of tears, and the nurses will be moved by me. They tell me: Don’t worry, we will be obedient, take good care of ourselves, and guard the triage desk to prevent the epidemic from entering the hospital.……I warned the young nurses that the best protection for patients is to guide patients with fever to follow the normal screening process and protect the environment of emergency treatment!

Emergency triage is the first pass for patients to see a doctor, and it is also the small peak of emergency treatment before the holiday. The daily emergency volume is as follows500Many times. Some patients don’t understand the process of fever screening, and they all come to the emergency room at the first stop; However, some patients are afraid of the fever clinic, unwilling to go to the fever clinic and go directly to the emergency department, which requires the triage nurse to do a good job in screening. Every day, the triage nurse takes pains to ask about the patient’s medical history, body temperature, whether there are flu-like symptoms, contact history in epidemic areas, etc. The triage nurse who screened out the fever patients will make a good registration, patiently explain and guide the patients to the fever clinic for screening. If the patient has no contact history with the epidemic area and has concerns about going to the fever clinic, the nurses will also take the initiative to escort the patient to the fever clinic to dispel the patient’s concerns.

To do a good job in emergency triage, we must be patient, careful and responsible. Niuxue—An old nurse in the emergency department is serious and experienced. At triage, a patient who had a history of traveling abroad caught her attention. Although the patient had a hospital visit a few days ago, she still didn’t relax, insisted on taking her temperature and asking about her medical history in detail, without ignoring every detail. The patient didn’t understand and didn’t want to go to the fever clinic. She took the initiative to report. Director Li Fengjie and I patiently worked for the patient, personally accompanied the patient to the fever clinic, and contacted the director of infection department to pay attention to this patient. It is precisely because of such high-quality and responsible emergency personnel that our emergency department is very safe!

onemoon22Day (December 28th)

I received an urgent notice from the hospital today, and the hospital is going to set up a medical echelon to build the Luhe River.—Isolation ward in Niubaotun campus. I sent a notice in the WeChat group, and everyone volunteered to sign up. To tell the truth, I really don’t know what young nurses are thinking now. However, to my surprise, the group immediately boiled up, from the old nurses in their fifties to the little nurses and advanced nurses who just joined the work, and everyone enthusiastically signed up. Zuo Feifei, an elderly male nurse in our department, was born less than a month ago in Erbao’s family, and her lover is in the hospital laboratory. He offered: At this moment, boys have to rush ahead! I quickly confided to him: the child is so young, does the family agree? Teacher Zuo seconds back: you can go at any time, no problem, mom and wife support it! Wang Xiaocui, a key nurse in Corey, is still breastfeeding and asked to go to the front line. She told me that she could go to the front line to work the night shift without breastfeeding! Yuan Wei, a young male nurse, didn’t work long. She sent a letter at the first time: Leader, I’m the first one. We boys are physically strong, so I’ll come first! Ji Jianjian: I spent a month in the A stream ward. I have experience. I’ll sign up! Teachers Zhang and Wang, who are in their fifties, are just like the children, unwilling to lag behind.……. Sitting in front of the computer, I can’t calm down for a long time, my eyes are wet, and my tears can’t help but stay. I posted a paragraph in the micro-group: I have experienced it.SARSI have felt the days of fighting side by side with my dearest friends and comrades-in-arms, and I have felt the most painful mental journey after my girlfriend got sick! Seeing everyone’s enthusiasm, full of emotion, and seeing the truth in times of crisis, thank you sincerely!

onemoon23Day (the 29th day of the twelfth lunar month)

The Spring Festival is coming, Wuhan is closed, and people all over the country are cheering for Wuhan! Yuan Wei, a nurse, got married this year. As a new uncle, she is going to pay a New Year call to her parents-in-law. After hearing the news, he immediately wrote to me: Leader, the situation is tense. I have returned my ticket and won’t go home. I’ll stay on duty or go to the front line, and my home work is done. Don’t worry!

Nurse Liu Xinrui made a New Year video entitled "The Best of Us" for everyone. In the video, we are fully armed and meticulously guarantee basic medical care for patients, and we can’t see their faces and smiles. At the end of the paragraph:2003The emergency department didn’t flinch in 1998,2020We are invincible in 2008! Yes, both mentally and technically, we emergency patients are ready! All of us are United as one to overcome the difficulties together. The emergency team is invincible, come on Luhe, come on Wuhan!

onemoon24Day (New Year’s Eve)

On this special Spring Festival, Chen Xu, the deputy head nurse, and I were on duty in the emergency room during the day shift and one at night! I can’t take care of the New Year’s greetings. I patrol the rescue room and triage desk over and over again, check the protection of on-the-job personnel, and guide patients and their families to wear masks. It is said that the masks on the market are out of stock, and the hospital leaders are very open-minded. All patients and their families who enter the emergency department will be provided free of charge without masks, and the doctors and patients will fight the epidemic together!

At six o’clock in the evening, director Xi Wei of the nursing department brought a New Year gift with the officers of the nursing department: a beautiful cup saidHappy holidays, hard work! It is very important to instruct us to make emergency triage, and guide the nurses to do a good job of protection. Although the director’s eyes are tired, his eyes are firm and give us confidence!

At eight o’clock in the evening, Dean Ji led the hospital leaders to pay a New Year call to everyone. The dean personally taught our young doctors and nurses how to wear masks and how to keep goggles from fogging. In the special period, the leaders are always careful and warm-hearted, which makes our frontline medical staff warm! The staff canteen brought jiaozi to everyone. Nurse Xu Ning said happily: jiaozi is particularly fragrant this year!

onemoon27Day (New Year’s Day)

Today, a patient was sent in, who had chest pain for some time and was afraid to come to the hospital for treatment. When he was sent to the emergency room, his breathing and heartbeat had stopped, and everyone refused to give up. He was wearing a thick mask, panting and sweating, and he had been doing cardiopulmonary resuscitation for a long time. How I hope to keep this young life!……

Faced with such a situation, it is understandable that patients are psychologically worried and everyone is afraid. The more special the period, the greater our responsibility. Just as the leaders of the hospital said, Luhe should have the spirit of responsibility in the face of the epidemic. While fighting the epidemic, we will ensure the basic medical care of the people in the region. Emergency personnel, cheer up, re-deploy our process, let the patients feel at ease, control the first level of emergency, and let the departments that accept patients have confidence. The patients who should be hospitalized will be admitted, and the moment of the operation will not wait!

Luhe—Niubaotun campus is about to be opened, and emergency doctors Jiang Zhifeng and Yue Xiaoyan are going to the isolation ward! Well done, emergency personnel. You are warriors and our pride!

onemoon29Day (New Year’s Eve)

The epidemic situation has developed rapidly. Many directors and head nurses in the hospital have not rested these days. Director Li Fengjie has been living in the hospital, coordinating the treatment of patients after fever clinic and emergency screening. An ambulance roared into the emergency room. A patient was breathing very weakly. Without any hesitation, Dr. Haotian Wang asked the medical history before screening others, and quickly rescued him. Only a senior nurse was left in the resuscitation room to cooperate with the emergency opening of the airway, and the rescue was done in one go! The family members thanked the medical staff for their rescue, saying that they had read a lot of reports about the epidemic recently, and the ambulance was worried that it would be complicated to go to the hospital to delay the rescue. Wang Dafu said: We are medical staff, no matter what the environment, saving people first! When the voice declined, the ambulance sent another patient with chest pain. He put down his unfinished medical record, began to review the electrocardiogram, opened a green channel, completed the screening process in the shortest time, and escorted the patient to the catheter room for emergency surgery. No matter what the environment, emergency medical staff will give priority to saving people, which is the responsibility and responsibility of our Luhe medical staff!

At three o’clock in the afternoon, the nursing department held an emergency meeting, and the superior informed Wuhan that there was a shortage of nurses to organize.21A reserve team of nurses supported Wuhan for a short time.360Many people signed up to support Wuhan, and Director Xi Wei shed tears of excitement. Our nurses are so cute, and Luhe is very happy with you! EmergencyN4Teacher Yan Jing and Xu Bolong, nurses, entered the big list and were ready to support Wuhan. Corey was boiling. The rest nurses moved half the materials from home and supermarket. Director Li Fengjie brought a whole bag of diapers at the first time, and Director Jin Aichun sent a pile of thick socks. Wuhan is wet and cold, so let’s wear warm clothes. Teacher Xie, the warehouse keeper, while counting the protective materials, told everyone not to waste reasonable protection. Let’s bring enough materials to the nurses who are about to go out! In the WeChat group, Teacher Yan Jing sent a message: I love you, I love you all, and I accept all the love. I feel that there is a smooth road ahead. Although I haven’t gone yet, with your love, my immunity has soared! Just go to work in another place, and everyone should take good care at home! Xu Bolong said: My grandfather was born in the army, and grandpa said, this is war!

These days, I feel more and more sentimental. My four-year-old daughter holds my arm every day when she goes out. I hope I can stay at home with her for one day. My daughter is very sensible because her father told her that her mother has an important job. See all kinds of greetings from relatives and friends on WeChat, see all kinds of information sent back by frontline colleagues, see the silent efforts of every Luhe person, see the information from time to time in Wuhan ahead, eat the hot soup noodles donated by the society, and we are full of gratitude for those who have no time to drink water! Love colleagues, love patients, love Luhe, we are strong emergency medical staff, as long as we have confidence, we will certainly win this epidemic war!

The steady operation of the Three Gorges Project on the Yangtze River provides strong support for the implementation of the national major strategy of "transmitting electricity from the west to the east". Photo by Zheng Jiayu/Bright Picture

In the workshop of Harbin Boiler Factory Co., Ltd., workers are carrying out production operations. Xinhua news agency

Farmers in Tangshan Agricultural Park, Hebei Province drive agricultural machinery to sow peanuts in the fields. Li Xiuqing photo/bright picture

　　A few days ago, "Opinions of the Central Committee of the Communist Party of China and the State Council on Accelerating the Construction of a National Unified Market" (hereinafter referred to as "Opinions") was released. The "Opinions" clarified the overall requirements, main objectives and key tasks of accelerating the construction of a unified national market from a global and strategic perspective, which quickly attracted social attention.

　　At present, why should China speed up the construction of a unified national market? How to understand the national unified market? How to promote the "Opinions" to be implemented and see actual results?

　　Promote China’s market from big to strong.

　　Nowadays, people can buy special products from all over the country through online shopping platforms without leaving home; New formats such as 5G remote consultation allow more patients in remote areas to enjoy quality medical resources; Some auto parts manufacturers can directly transmit the technical drawings to the supplier’s production line & HELIP; &hellip;

　　"It should be noted that the rapid development and extensive penetration of next-generation information technologies such as big data and artificial intelligence are destroying all kinds of market barriers and barriers, which is of revolutionary significance for building a unified national market." Wang Yiming, vice chairman of China International Economic Exchange Center, said.

　　According to Zhong Maochu, a professor at the Institute of Economics of Nankai University, the national unified big market is a product such as land, labor, capital, technology, data, resources, and goods and services, which has formed an unmanned market among different regions, industries, groups, large and medium-sized enterprises, state-owned enterprises and private enterprises nationwide.

　　In recent years, important progress has been made in the construction of the national unified big market, but there are still some problems that hinder the construction of the national unified big market in practice.

　　Wang Yiming introduced that since the 18th National Congress of the Communist Party of China, China has adhered to the direction of socialist market economy reform, promoted market-oriented reform in breadth and depth, constantly improved systems of property rights protection, market access and fair competition, promoted price reform and market-oriented reform of important production factors such as land, capital, labor force, technology, knowledge and data, eliminated market barriers, and accelerated the formation of a modern market system.

　　"The scale of China’s domestic market ranks among the best in the world, and the scale advantage of commodity market is obvious. The scale of capital, technology, data and other factor markets is expanding rapidly, but market segmentation and local protection are more prominent, market competition is insufficient, the development of factor markets is lagging behind, and the market operation efficiency is not high. The supervision method needs to be innovated." Wang Yiming said.

　　In this regard, the "Opinions" propose to speed up the establishment of unified national market system rules, break local protection and market segmentation, open up key blocking points that restrict the economic cycle, promote the smooth flow of commodity elements and resources in a wider range, and accelerate the construction of an efficient, standardized, fair competition and fully open national unified market.

　　As the relevant person in charge of the National Development and Reform Commission said, the Opinions provide a program of action for building a unified national market in the coming period, which will certainly have an important impact on deepening reform and opening up under the new situation, making better use of the tremendous advantages of exerting, consolidating and enhancing China’s market resources, and comprehensively promoting the transformation of China’s market from large to strong.

　　Dong Yu, executive vice president of Tsinghua University China Institute of Development Planning, believes that at present, the difficulties and challenges in economic work are increasing. The central government’s layout will accelerate the construction of a unified national market, which will play a vital role in stabilizing the confidence of market players and thus stabilizing the overall development.

　　Building a high-level market circulation system

　　At present, some people have misunderstandings about the connotation, goal and realization path of the national unified market. For example, some people think that "building a unified national market means the return of the planned economy". This is a representative erroneous view.

　　"We must realize that the biggest comparative advantage of China’s economic development today is its large-scale domestic market and strong domestic demand potential." Yao Jingyuan, a special researcher in the State Council Counselor’s Office, said that building a unified national market is not a return to the planned economy, but a strong support for building a high-level socialist market economic system.

　　Chen Weiwei, an associate researcher at the Institute of Economic System and Management of the National Development and Reform Commission, said that the most striking feature of the planned economy is that enterprises produce according to the planned instructions, and their products are distributed and sold through unified channels. The purpose of building a unified national market is to get rid of market barriers and maintain fair competition. The logic behind it is to build a national big market with unified rules and regulations for all kinds of market entities and encourage diversified market entities to enter the market for fair competition; Industry authorities and local governments should not "bias", but really give "unique skills" and responsible enterprises a broader stage, and really let market price signals play a role in optimizing the allocation of resources.

　　"It can be seen that building a unified national market is not about unifying market players, distribution channels, goods and services, market prices, and nationalization." Chen Weiwei said.

　　Guo Liyan, a researcher at China Macroeconomic Research Institute, believes that a strong domestic market not only refers to a larger scale, but also refers to a modern market circulation system with more complete institutional rules, more optimized structural levels and stronger influence and attraction. This is the core energy to actively allocate domestic and foreign factor resources, a powerful engine to drive high-quality economic development, and a complete system to promote the dynamic balance between supply and demand of the national economy at a higher level and level.

　　"China has obvious advantages of super-large scale and overall market, which is an important advantage and key support for China to actively participate in reshaping the global competition pattern." Guo Liyan said that the "key measure" to comprehensively stabilize the smooth circulation of the domestic economic system is to speed up the construction of a unified national market, further cultivate and stimulate the potential of the domestic market, and resist the challenges of external uncertainty with maximum certainty.

　　Break all kinds of closed small markets

　　"The market is the bridge connecting supply and demand, the space for enterprises to compete and play games, and the realization of products and services &lsquo; The most thrilling leap &rsquo; 。” Chen Weiwei said that at present, China’s domestic market is large but not strong, and there is still great potential to be tapped. Building a unified national market can give full play to the advantages of China’s ultra-large-scale market, cultivate local world-class enterprises, attract resources with global advantages, and enhance the international discourse power of China’s market.

　　In terms of the main objectives, the Opinions clearly state that the domestic market will continue to be efficient, smooth and scale-expanding, and a stable, fair, transparent and predictable business environment will be accelerated, so as to further reduce market transaction costs, promote scientific and technological innovation and industrial upgrading, and foster new advantages in participating in international competition and cooperation.

　　It is understood that the National Development and Reform Commission and the General Administration of Market Supervision will work with relevant departments to establish and improve the departmental coordination mechanism to promote the construction of a unified national market and increase overall coordination. At the same time, clarify the phased work objectives, solve outstanding problems, and promote the reform measures to be effective as soon as possible.

　　"The key is to persist in making breakthroughs at the same time and pressing ahead. For the outstanding contradictions and problems facing the reform, we must resolutely break it and escort the overall stability with the point of reform." Dong Yu said that in order to standardize market intervention and create a stable, fair, transparent and predictable business environment, it is necessary to truly implement the concept of taking the needs of market participants as the guide and practicing the principle of simplicity, create a good ecology for all kinds of market participants to invest and start businesses, and make the process of building a unified big market become a process of constantly standardizing government behavior and reducing market intervention.

　　In Wang Yiming’s view, it is necessary to promote the construction of a unified national market through reform and innovation. To unify the rules of the market system, we should adhere to the problem-oriented principle and make innovations at the same time. We should not only deepen the reform, but also strengthen the unity of the rules of the system and the consistency of supervision and law enforcement on the basic components such as property rights system, market access, fair competition and market supervision, and also speed up the elimination of various regulations and practices that hinder the unified market and fair competition.

　　Guo Liyan said that all localities and departments should improve their positions, focus on the overall situation, obey the overall situation, give full play to the advantages of the whole country in playing a chess game and concentrating on major events, and resolutely get rid of the wrong understanding and practice of "warlord separatism" among regions and engaging in local small circulation in their own way, get rid of all kinds of closed small markets, and open up the economic cycle between different regional spaces such as "blocks", "provinces" and "cities" and "urban and rural areas".

　　CCTV News:From June to August, 2016, a telecom fraud gang committed fraud crazily. During this period, Cai Shuyan, a college student, committed suicide by jumping into the sea after being defrauded of tuition and living expenses of 9800 yuan. On the morning of 28th, the Intermediate People’s Court of Jieyang City, Guangdong Province sentenced seven defendants, including Chen Minghui, to life imprisonment and three years’ imprisonment.

　　The court found through trial that from August 2013 to March 2014, Chen Minghui repeatedly hired Tang Xiaohui (sentenced) to pretend to be a variety show such as "Where is Dad?" and sent more than 730,000 false winning fraud messages to mobile phone users.

　　From June to August, 2016, Chen Minghui recruited and assembled Fan Zhijie, Gao Xuezhong, Ye Qifeng, Xiong Yunjiang and others to form a criminal gang. By sending false winning information such as "Taobao" and "Run Brothers", he induced the winners who received the information to log in to the "phishing website" to fill in their personal information to receive the prize, and pretended to be a customer service staff to trick the winners into paying the "deposit" on the grounds of redemption. Pretending to be court staff and lawyers, it is a breach of contract that the "winner" fails to pay the "security deposit" or receive the prize as required. It is necessary to sue or have sued the "winner" and continue to pay the handling fee before withdrawing the lawsuit and obtaining the prize, threatening and luring, and defrauding the "winner" again, defrauding many people of property totaling RMB 1.041 million. Among them, Cai Shuyan, a student about to attend university, committed suicide by jumping into the sea after being defrauded of tuition and living expenses of 9800 yuan.

　　The court also found that Lin Shiya knowingly engaged in illegal and criminal activities by Ye Qifeng and others, and still illegally entrusted him with point-of-sale terminal equipment (POS machines), which provided convenient conditions for him to cash in the stolen money. Knowing that others are engaged in illegal and criminal activities, Chen Liyi still sells several bank cards to others for fraud. In addition, Xiong Yunjiang was caught by the traffic police for drunk driving in Haikou.

　　The court held that in the joint crime of fraud, Chen Minghui, Fan Zhijie, Gao Xuezhong, Ye Qifeng and Xiong Yunjiang, for the purpose of illegal possession, formed a telecom fraud criminal gang, used communication tools and online means to defraud an unspecified majority of people, and caused a student to commit suicide. The amount of fraud was particularly huge and the circumstances were particularly serious, all of which constituted fraud. Xiong Yunjiang also drunk driving a motor vehicle on the road, and his behavior constitutes a crime of dangerous driving, which should be combined with several crimes according to law. Knowing that others commit crimes, Lin Shiya has repeatedly provided point-of-sale terminal equipment (POS machines) to help transfer the proceeds of crimes. Knowing that others commit crimes, Chen Liyi still provides multiple bank accounts for others to transfer the proceeds of crimes, which has constituted the crime of concealing and concealing. According to the facts, nature, circumstances and the degree of harm to society of each defendant, the Intermediate People’s Court of Jieyang City, Guangdong Province sentenced the defendant Chen Minghui to life imprisonment, deprived of political rights for life and confiscated all personal property. The defendants Fan Zhijie, Gao Xuezhong and Ye Qifeng were sentenced to fixed-term imprisonment ranging from 15 to 13 years and fined for fraud; The defendant Xiong Yunjiang was sentenced to 11 years in prison and fined for fraud and dangerous driving. The defendant Lin Shiya was sentenced to three years’ imprisonment and the defendant Chen Lucy li was sentenced to one year and four months’ imprisonment and fined for concealing and concealing the crime. The defendants were ordered to jointly refund the fraudulent money to the victim.

　　CCTV News:On October 21st, 2017, coincided with the grand opening of The 19th National Congress of the Communist Party of China, the 23rd China Yiwu International Commodities Fair, the largest commodity fair in China, was held in Yiwu, Zhejiang.

　　This year’s Yiwu Fair has 4,100 standard booths, involving 14 major industries. Combining with the cultivation direction of emerging sectors, it has set up eight special areas, namely "Made in Zhejiang" theme area, standard Expo area, innovative design, smart lifestyle, fashion department stores, international brands, e-commerce and trade services, and women’s Federation handicrafts, with a total of 10 pavilions with an exhibition area of 100,000 square meters. It attracted more than 2,200 enterprises from 16 countries and regions including Australia, Japan, Brazil, Germany, Italy and France, as well as 24 provinces (municipalities and autonomous regions) in China.

　　As an important supporting meeting in the 2017 Yiwu Fair, the "2017 China Retail Department Store (Yiwu) Purchasing Summit" was held simultaneously during this period. The summit was hosted by the Executive Committee of Yiwu International Commodity Expo in China, jointly organized by Zhejiang China Commodity City Group Co., Ltd. and IBMG International Business Management Group, and sponsored by Yiwu Mr. Huolang Trading Co., Ltd., and the conference received extensive attention and praise from the government, industry, news media and people from all walks of life.

　　More than 200 enterprise bosses and senior executives from more than 50 retail enterprises, including national top 100 retail enterprises, listed companies and regional leading enterprises, led their professional purchasing teams to participate in the summit. In order to actively broaden the domestic sales channels of local suppliers in Yiwu, improve the purchasing efficiency and quality of participating retailers, and promote the in-depth cooperation between suppliers and retailers, the summit invited Mr. Li Sheng, deputy director of the Expert Working Committee of China Business Federation, Professor Wu Leijun, course director of SPACE China Business College of the University of Hong Kong, and other big coffee makers in the retail industry to conduct in-depth thematic discussions and share, and specially arranged a number of on-site retailers’ fair for high-quality goods, which promoted many categories such as household goods, imported goods, knitwear, toys, cultural offices and sporting goods. During the summit, the delegates also visited well-known local enterprises in Yiwu, and went deep into the factory to learn about commodity technology.

　　Mr. Jiang Ming, President of China Business Federation, made an opening speech for the summit.

　　In his opening speech, Mr. Jiang Ming, President of China Business Federation, said: Yiwu has changed from "buying and selling the whole country" to "buying and selling the whole world". This is a hot spot for entrepreneurship, a land of real miracles. Department stores cover a wide range of commodities, and have become synonymous with Yiwu. Yiwu International Trade City is one of the largest export bases of small commodities in China, and its market extroversion has reached 65%.

　　The theme of this conference, "focusing on commodities, upgrading layout-supply chain reconstruction under consumption upgrading", fits the background of the retail industry environment, identifies the profit model, returns to the essence of retail, and locates customers with commodities. This summit will discuss how to rebuild the supply chain in the new retail era with the help of Yiwu’s advantages, new technologies and new theories, focus on market consumers, push forward with the pace of transformation of both domestic and foreign trade in Yiwu Fair, and strive for the healthy and rapid development of the retail industry and a broader future!

On December 30, 2020, Beijing Institute of Biological Products Co., Ltd. quietly published a short announcement in official website. According to the interim analysis results of Covid-19 inactivated vaccine phase III clinical trial, the safety of Covid-19 inactivated vaccine of China Bio-Beijing Company of Sinopharm Group was good after inoculation.After two doses of immunization, the positive conversion rate of neutralizing antibody was 99.2%, and the protective power of vaccine against diseases caused by COVID-19 infection (Covid-19) was 79.34%.

Prior to this, Pfizer and Moderna from the United States also released the research results of phase III clinical trials of their own mRNA vaccines, and the protective power was over 90%. In this way, our vaccines seem to have a little poor protective effect. But be careful,This is not because our technology is not good, but more because of the congenital difference between mRNA vaccine and inactivated vaccine.

Immune protection induced by inactivated vaccine is relatively weak.

Inactivated vaccine is a vaccine made by inactivating virus by physical or chemical methods. Compared with live virus particles, the immunogenicity of inactivated virus is relatively weak, and adjuvant is often needed.

In 2013, a study entitled "Characterization of immune responses induced by activated, live attended and DNA vacuums against Japanese encephalitis virus in mice" was confirmed by Japanese encephalitis virus.Compared with artificial attenuated live vaccine and DNA vaccine, the immune response induced by inactivated vaccine is relatively weak.

Figure 1. Heading of the article

The researchers divided the mice into four groups, injected with inactivated vaccine (INV), live attenuated vaccine (LAV), DNA vaccine (pCAG-JME) and control, and then detected the antibody level in mice. At the end of the experiment, the total antibody titer induced by inactivated vaccine was significantly lower than that of attenuated live vaccine group and DNA vaccine group.

Fig. 2 Antibody level pairs induced by three vaccines

The researchers also detected the levels of different subtypes of IgG induced in the serum of mice, and found that there were differences among the three vaccines. The inactivated vaccine mainly induced IgG type 1 antibody, while the attenuated live vaccine mainly induced IgG type 2a antibody, and the antibody levels of DNA vaccine were both high.

Fig. 3 Different IgG subtypes induced by three vaccines

The researchers also compared the levels of cytokines induced by vaccine and the levels of dendritic cells and Treg in detail, and there were some differences. Anyway,There are some differences in immune response induced by inactivated vaccine, attenuated live vaccine and nucleic acid vaccine. It is not surprising that the protective effect of inactivated vaccine is not as good as that of RNA vaccine.

Inactivated vaccine has the best safety.

Because the clinical data of phase III vaccine of Beijing Institute of Biological Products have not been published in any authoritative journals,Therefore, the safety of inactivated vaccine BBIBP-CorV in China, mRNA vaccine BNT162b2 in Pfizer and mRNA vaccine mRNA-1273 in Moderna Company are examined from the published phase I/II clinical trials of vaccines.Someone has made statistics on the safety data of phase I/II clinical trials of various COVID-19 vaccines, and all the data are shown in the following figure. After the first dose of mRNA-1273 vaccine was injected, the incidence of systemic grade I adverse reactions was 53.3%, grade II adverse reactions were 13.3%, local grade I adverse reactions were 73.3%, and grade II adverse reactions were 13.3%. After injecting the second dose, the incidence of systemic first-class adverse reactions was 20%, and the incidence of second-class adverse reactions was 80%. The incidence of local first-class adverse reactions was 66.7%, and the incidence of second-class adverse reactions was 26.7%. No adverse reactions above grade 3 were found locally or systemically.

However, after injection of Pfizer’s BNT162b2, the incidence of local or systemic adverse reactions was 41.7%, and the incidence of adverse events above grade 3 was 8.3%. For people aged 65-85, the incidence of local or systemic adverse reactions is 25%, and the incidence of adverse reactions above grade 3 is 8.3%.

The results of phase I clinical trial of domestic inactivated vaccine BBIBP-CorV in China show that the incidence of first-grade local or systemic adverse reactions is 33% for people aged 18-59, and that of second-grade adverse reactions is 13%. For people over 60, the incidence of adverse reactions is 29%, and there are no adverse events above grade 3. In the results of Phase II clinical trials, the incidence of Grade I adverse events was 15%, and the incidence of Grade II adverse events was 2%.

Fig. 4 Adverse reactions of various vaccines.

Judging from these data, among the three popular vaccines at present, the safety of inactivated vaccine in China is absolutely the best, not to mention the recent allergic storm of Pfizer vaccine, which has caused rare allergic reactions in dozens of people.

Domestic vaccines with 79% protection and no serious adverse reactions are absolutely safe and effective.Because China’s epidemic prevention and control work is very well done, we have to overcome many difficulties when conducting clinical trials of vaccines. After all, the epidemic situation in COVID-19 is well controlled and there is no condition for clinical trials, which is one of the reasons why the progress of phase III clinical trials lags behind others. We should see that even if our protection efficiency does not exceed 90% in the United States, inactivated vaccine obviously has advantages, such as it is safer and easier to store and transport. Although our protective effect is not as good as the two vaccines in the United States, it has reached the standard of vaccine approval, and the protective effect far exceeds 50%, which is trustworthy.

Beijing Zhengban made [1995] No.20

The people’s governments of the districts and counties, the commissions, offices and bureaus of the municipal government, and the municipal institutions:

　　In order to meet the needs of the construction of the socialist market economic system, speed up the construction of the market system in this city, strengthen the macro-control of the municipal government on the agricultural products market, and prosper and stabilize the agricultural products market in the capital, the municipal government has decided to set up the Beijing Central Wholesale Market Management Committee of Vegetables, Fruits and Flowers, which is a fairly bureau-level institution sent by the municipal government to act as the relevant administrative functions of the municipal government.

　　The main duties of the Beijing Central Wholesale Market Management Committee of Vegetables, Fruits and Flowers are: to formulate and organize the implementation of the phased planning and construction plan according to the overall market plan determined by the municipal government, and to handle matters such as land expropriation, project development, land use right transfer, relocation and resettlement of farmers (residents) and enterprises within the overall market plan; In conjunction with relevant departments, review and handle the project initiation, feasibility report, contract articles of association, architectural design and construction of construction projects within the market, and examine and approve various enterprises and import and export agency business in the market; Supervise and manage enterprises and institutions in the market according to law; To study and formulate specific policies, systems and measures for the development, construction, operation and management of this market.

　　The internal organization of Beijing Central Wholesale Market Management Committee of Vegetables, Fruits and Flowers shall be separately approved by the Municipal Compilation Office.　

　　March 25, 1995　　

In February, 2021, new york Mayor’s Food Policy Office released the first 10-year food policy plan "NYC: A 10-year food policy plan". This series consists of seven articles, translated by the team of "the other mountains all appear dwarfs under the sky.-Sustainable City and Transportation". This is the fourth article, which introduces the second goal of new york’s ten-year food policy plan: to make new york’s food economy promote economic development and provide good jobs.

New york has more than 40,000 food enterprises, employing hundreds of thousands of workers. It is difficult to calculate the exact number of workers, because there is no reliable data to explain the number of workers in the "gig economy" in food distribution. These workers and enterprises are vital to the health and well-being of new york people. The food industry is an important source of employment and property income for colored people and immigrant communities (79% of food workers in new york are colored people, including 43% Latinos and 21% Asians).

The catering industry is also very important to the city, because it is the main attraction of residents, workers and tourists, supporting many other industries, such as office employment in the central business district and attracting tourists. In fact, the catering industry is the key to making new york so attractive. Its economic contribution is also great. In 2019, the taxable sales of the catering industry reached nearly $27 billion.

However, working in the food industry or owning a business is extremely challenging. The food industry usually has a low profit margin, while the cost of running a business in new york is high. About 99% of food enterprises in the city are small enterprises with less than 100 workers, while 70% are micro enterprises with less than 10 workers. In addition, the wages of food workers are usually low, and they lack job security and mobility opportunities. Many deliverymen (an increasingly important part of the food industry) are considered as independent contract workers and cannot get the same protection and benefits as employees.

If new york wants to improve its food system, it must first support both food workers and food enterprises. The support for the two is not mutually exclusive, but mutually reinforcing. These strategies also focus on the future of food enterprises, including supporting a new ownership model that conforms to the principles of economic democracy and technological change.

Size of food enterprises in new york (calculated by number of employees). Cartography: the other mountains all appear dwarfs under the sky., the picture is from NYC Food Forward, only translated in Chinese.

Strategy 1: Protect the rights and interests of food practitioners　

Implementing fair scheduling method in fast food industry

New york will strictly implement the fast food fair scheduling laws, so as to optimize the fast food industry into a benign occupation with stable and predictable working hours and wages. Strong law enforcement will ensure that workers in fast food restaurants can arrange shifts fairly and even get overtime pay when the shift schedule is temporarily changed. Law enforcement will also ensure that workers in the fast food industry can settle down through regular shifts in high-mobility industries.

Provide financial and technical support for workers’ cooperatives

The cooperative model has a long history in the food field. Worker-owned cooperatives have yet to become a powerful tool for new york to accumulate assets and eliminate the gap between the rich and the poor. In order to meet the needs of food enterprises, new york will not only coordinate existing auxiliary projects to support cooperatives, such as Employee Ownership, but also explore innovative financial and technical support projects.

When it is not appropriate for the government to directly intervene in enterprises, the New York City Government will also explore cooperation with community-based organizations, business improvement areas (BID) and merchant associations, and provide support for cooperative organization efforts in five administrative regions.

Improve the situation of food workers.

New york will promote a series of state and federal bills to improve the situation of workers in the food industry, as listed below:

(1) Ensure that all employees in the food industry are included in the federal and state welfare plans;

(2) For employers who fail to protect workers’ health, abolish relevant laws that limit their responsibilities;

(3) Change the state regulations on tip pool sharing, and expand the scope of employees who participate in tip sharing, so that employees without tips can also get some sharing;

(4) To cope with emergencies, set up a hazard pay for grass-roots food workers.

Provide support to practitioners of food programs.

New york will make efforts to provide support to practitioners of food programs. Under the circumstance that the purchasing power is restricted by the current laws, new york will first ensure that food suppliers abide by the current labor laws and collect more labor-related information from food suppliers. In addition, new york will promote the revision of applicable laws and use food procurement power to optimize the working conditions of food practitioners.

Expand child care services to solve the problem of night care for children of food practitioners.

During the COVID-19 crisis, new york deeply realized the hard work and important role of food practitioners. Child care has been provided through the Regional Enrichment Centers "and child care programs throughout the city. With the gradual recovery of the city, existing facilities for childcare projects will be expanded or new projects will be created, including night and weekend care, which is the time when children need care most and parents are most inconvenient to take care of. Providing night and weekend child care will enable parents who often work at night and weekend classes to improve their work flexibility and reduce the cost of childcare.

Feasibility study on developing basic social security benefits

New york will conduct a feasibility study on the basic social security benefits for all food workers. This study will explore the potential partnerships among food practitioners, enterprises, community organizations and financial institutions. This project focuses on providing welfare protection such as pension and medical insurance for food practitioners. New york will also push the federal government to introduce a bill to provide full and fair social security benefits for all employees, regardless of their employers, workplaces or job nature.

Strategy 2: Simplify the process, encourage innovation and support small food enterprises.

Promote tax credits for small businesses.

New york will promote state legislation and establish a tax deduction mechanism for small businesses, including the food industry, to promote the recovery of small businesses in new york. Eligible enterprises with a total income of less than $1 million will receive a tax credit of 6% of their rent in 2021, with a maximum tax credit of $10,000.

Simplify the related processes of food enterprises

New york will review the regulations and enforcement procedures related to small food enterprises (including street vendors) to streamline the process. New york will improve efficiency as much as possible, and expand consolidated licensing and inspection services, so that simplified processes can benefit start-up and existing small food enterprises. The municipal government will also carry out innovation in matters related to food enterprises and increase opportunities for participation, especially cooperation with immigrant organizations.

Support the food enterprises of new york Housing Bureau.

New york will cooperate with enterprises and community organizations to expand the Food Business Pathways of new york Housing Bureau (NYCHA). The establishment of the Business Accelerator Program aims to enable residents of the public housing development project of new york Housing Bureau and those who hold the Class 8 housing clause subsidy voucher of new york Housing Bureau (note: the subsidy voucher program was established in 1978 to provide assistance to eligible low-and middle-income families in renting houses from private hands) to start and develop food business.

Promote the protection of food property and customer data.

The successful operation of food business relies more and more on the data of third-party providers. However, food enterprises often lack professional knowledge or the ability to use these services on favorable terms, and may not be able to obtain key information such as customer data. New york has convened a number of stakeholders to jointly promote initiatives to protect the data of food enterprises and customers, such as the "data bill of rights" for food enterprises and customers.

Support the needs of food enterprises and cooperatives

New york will convene stakeholders in the food industry to identify and design new projects to meet the special demands of food enterprises and non-profit organizations. New york City will then promote the effective implementation of these projects by the state and federal governments. This may include developing new financing and technical assistance programs to help mutual-help and self-operated workers’ cooperatives and small food enterprises.

Suppliers are more likely to participate in the urban procurement process.

New york will promote the smooth connection between potential food suppliers and the urban procurement process. PASSPort, a digital procurement portal in new york, will launch new functions to improve the procurement process. Including: simplifying the collection process, speeding up the issuance of invoices, improving transparency more widely and promoting cross-departmental cooperation.

In addition, new york will explore ways: using matchmaking tools and group buying strategies to increase the number of bids for urban food contracts; Expand technical support and guide the procurement process; Provide process navigator to assist small suppliers in the procurement bidding process; And explore to simplify the application process of M/WBE (note: M/WBE: minority and women-owned business enterprises, enterprises owned, operated and controlled by ethnic minorities and women).

Strategy 3: Help the next generation of food workers get high-quality jobs.

Launch a community recruitment plan for the food industry.

New york will use the current new york NYC plan and the proposed Community HireNYC Legislation to expand the recruitment demand, and set up good entry-level posts in the whole food procurement process, including food production, distribution, transportation and other related work.

New york will combine the existing and new training plans to provide human resources for suppliers, and require suppliers to provide interviews and employment opportunities for qualified low-income people. New york will also cooperate with anchor institutions to expand the number of high-quality entry-level jobs in food procurement, and pay special attention to core institutions in underserved communities.

Support food technology vocational training

New york’s partners in catering, manufacturing and industry will continue to keep pace with the technological upgrading of the industry. These partners will provide advice to small business service organizations (SBS) on the development of specific labor force and provide new technology training programs for industry practitioners. This can ensure that employees are at the forefront of technological change and that they learn new skills at work, rather than being replaced by new technologies.

Create and expand the career path of food practitioners

New york will ensure the prospect and "Qian Jing" of food industry, both warehouse workers and kitchen staff can be developed, and provide more training, certification and business plans for food practitioners.

Listed below:

(i) Expand training and entrepreneurship programs for commercial kitchens, such as the First Course NYC and Food Business Pathways in new york;

(ii) providing English as a Second Language services for non-native English-speaking food workers;

(iii) Cooperating with the industry to provide the US Department of Energy (DOE) vocational and technical education courses for practitioners in food production, processing, storage and distribution processes;

(iv) Linking youth training programmes with career paths;

(v) Explore the curriculum options of NYC Health Department’s Health Academy of new york Municipal Health Bureau, which is a labor force development center that provides food safety training for food practitioners.

Make a development plan for campus food practitioners

To provide the healthiest and freshest food for students in new york, well-trained practitioners are essential. New york will cooperate with academic circles and the private sector to provide accurate and comprehensive training courses for all school food managers. Training topics include but are not limited to: leadership skills, storage and organization, knife skills, use of tools and equipment, basic cooking skills, menu planning and food preparation. New york will also make an in-depth analysis of the current training programs to see if it is necessary to upgrade.

(This article was translated by the team of "the other mountains all appear dwarfs under the sky.-Sustainable City and Transportation" and checked and edited by The Paper. Translators: Lin Ruoran, Guo Yue, Hao Lu, Jin Yutong, Lei Lian, Lu Yating, Sun Yuting, Tang Hui, Yang Xiaohan, Yang Shasha, Yi Siqing, Zhou Jin, revisers: Xiang Xinyi, Liu Daizong. )